Publications

    Anti-Streptococcus mutans therapeutic development

  1. He J, Anderson M, Shi W, Eckert R. Design and activity of a 'dual-targeted' antimicrobial peptide. International Journal of Antimicrobial Agents, 2009 Jun;33(6):532-7


  2. He J, Eckert R, Pharm T, Simanian MD, Hu C, Yarbrough DK, Qi F, Anderson MH, Shi W. Novel synthetic antimicrobial peptides against Streptococcus mutans. Antimicrob Agents Chemother, 2007 Apr;51(4):1351-8. Epub 2007 Feb 12


  3. Eckert R, He J, Yarbrough DK, Qi F, Anderson MH, Shi W. Targeted killing of Streptococcus mutans by a pheromone-guided "smart" antimicrobial peptide. Antimicrob Agents Chemother, 2006 Nov;50(11):3651-7.


  4. Li L, He J, Eckert R, Yarbrough D, Lux R, Anderson M, Shi W. Design and characterization of an acid-activated antimicrobial peptide. Chemical Biology & Drug Design, 2010 Jan;75(1):127-32


  5. He J, Yarbrough DK, Kreth J, Anderson MH, Shi W, Eckert, R. A systematic approach to optimizing specifically-targeted antimicrobial peptides against Streptococcus mutans. Antimicrob Agents Chemother, 2010May;54(5):2143-51. Epub 2010 Mar 8.


  6. Li L, Guo LH, Lux R, Eckert R, Yarbrough DK, He J, Anderson M, Shi W. Targeted Antimicrobial Therapy Against Streptococcus mutans Establishes Protective Non-cariogenic Oral Biofilms and Reduces Subsequent Infection. International Journal of Oral Science, 2010 April;1(2):66-73


    7. Anti-Pseudomonas aeruginosa therapeutic development

  7. Eckert R, Mchardy I, Yarbrough DK, He J, Qi F, Anderson MH, Shi W. Stability and activity in sputum of G10KHc, a potent anti-Pseudomonas antimicrobial peptide. Chem Biol Drug Des, 2007 Nov;70(5):456-60. Epub 2007 Oct 10.


  8. Eckert R, Brady KM, Greenberg EP, Qi F, Yarbrough DK, He J, McHardy I, Anderson MH, Shi W. Enhancement of antimicrobial activity against pseudomonas aeruginosa by coadministration of G10KHc and tobramycin. Antimicrob Agents Chemother, 2006 Nov;50(11):3833-8.


  9. Eckert R, Qi F, Yarbrough DK, He J, Anderson MH, Shi W. Adding selectivity to antimicrobial peptides: rational design of a multidomain peptide against Pseudomonas spp. Antimicrob Agents Chemother, 2006 Apr;50(4):1480-8.


    10. Biomineralization Peptides

  10. Yarbrough DK, Hagerman E, Eckert R, He J, Choi H, Cao N, Le K, Hedger J, Qi F, Anderson M, Rutherford B, Wu B, Tetradis S, Shi W. Specific binding and mineralization of calcified surfaces by small peptides. Calcified Tissue International, 2010 Jan;86(1):58-66


    11. Botanicals: Herbal Lollipop

  11. He J, Chen L, Shi W, Lu, Q-Y. Antibacterial compounds from Glycyrrhiza uralensis. Journal of Natural Products, 2006 Jan;69(1):121-4.


  12. Belt, D. Licorice root lollipop shows sweet promise in reducing tooth decay. Journal of the California Dental Association, 2008 Apr;36(4):243,249.


  13. How Many Licks Does it Take to Reduce Tooth Decay? Delta Dental press release on two clinical studies with the herbal lollipop, 2008 Sep. [Update Sept 09: Clinical study results are positive and a publication has been accepted by the Journal of Functional Foods. Manuscript will be posted after publication]